{"id":9383,"date":"2022-05-31T15:30:04","date_gmt":"2022-05-31T05:30:04","guid":{"rendered":"https:\/\/metronorth.health.qld.gov.au\/staff-news\/?p=7153"},"modified":"2022-10-27T16:23:22","modified_gmt":"2022-10-27T06:23:22","slug":"epilepsy-treatment","status":"publish","type":"post","link":"https:\/\/metronorth.health.qld.gov.au\/extranet\/newsletters\/news-at-the-royal\/epilepsy-treatment","title":{"rendered":"Mini-brains revolutionise epilepsy treatment"},"content":{"rendered":"
\"RBWH

RBWH Neurology Senior Staff Specialist and University of Queensland Neurosciences Theme Leader Associate Professor Lata Vadlamudi is leading the way in epilepsy research.<\/p><\/div>\n

Researchers at RBWH and the University of Queensland (UQ) are trialling a new technology set to help epilepsy patients find the best treatment for their condition sooner.<\/h4>\n

One in 26 Australians will develop epilepsy in their lifetime and more than 30 per cent of these people do not respond to anti-seizure medications. Often, the journey to find a medication or combination of medications that successfully control an individual\u2019s seizures can take many years of trial and error.<\/p>\n

In conjunction with researchers at RBWH and UQ, stem cell biologists are using advanced technologies to grow human stem cells from epilepsy patients into organoids in the lab, otherwise known as \u2018mini-brains’. Researchers are then able to test different anti-seizure medications on the organoids to see if these cells mirror how patients react to the medications. If successful, it will revolutionise the way drugs are selected for epilepsy patients.<\/p>\n

RBWH Neurology Senior Staff Specialist, Metro North Health Clinician Fellow and University of Queensland Neurosciences Theme Leader Associate Professor Lata Vadlamudi said ongoing seizures have a huge impact on quality of life for patients.<\/p>\n

\u201cThe prospect of shortening the tumultuous journey many epilepsy patients must undertake to find the right medication is incredibly exciting,\u201d she said.<\/em><\/p>\n

\u201cFor some patients, the process of finding a medication that works can be a rollercoaster, trialling drug after drug in the hope of improving their seizures. There is disappointment and distress each time a drug fails to improve their condition, as well as potential side-effects with each drug trialled.<\/em><\/p>\n

\u201cThis can have an enormous toll on patients\u2019 physical and psychological condition, resulting in a reduced quality of life and increased risk of sudden unexpected death associated with epilepsy.<\/em><\/p>\n

\u201cWe are optimistic our research will result in a major step forward in epilepsy treatment.\u201d<\/em><\/p>\n

Aaron Reid, aged 38, is an epilepsy patient at RBWH and has experienced firsthand the difficulties associated with finding the right medication to control his epilepsy seizures.<\/p>\n

\u201cI was diagnosed with epilepsy at age 11 when I had a seizure while swimming. I don\u2019t remember anything, but I\u2019m told I just sunk straight to the bottom of the pool,\u201d Aaron said.<\/em><\/p>\n

\u201cI\u2019ve been on various medications since that day to try and control my seizures. Medication often works for a few years before I start suffering seizures again and am required to try something new.<\/em><\/p>\n

\u201cI\u2019ve started experiencing nocturnal seizures in the past few years and am currently taking five different kinds of medication to try and control them. Nothing is working yet.<\/em><\/p>\n

\u201cNew treatment options like this really make me feel like there\u2019s light at the end of the tunnel.\u201d<\/em><\/p>\n<\/div>

<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

Researchers at RBWH and the University of Queensland (UQ) are trialling a new technology set to help epilepsy patients find the best treatment for their condition sooner. <\/p>\n","protected":false},"author":53,"featured_media":10404,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_searchwp_excluded":"","footnotes":""},"categories":[176],"tags":[],"class_list":["post-9383","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-at-the-royal"],"acf":[],"yoast_head":"\nMini-brains revolutionise epilepsy treatment - Staff Extranet<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mini-brains revolutionise epilepsy treatment - Staff Extranet\" \/>\n<meta property=\"og:description\" content=\"Researchers at RBWH and the University of Queensland (UQ) are trialling a new technology set to help epilepsy patients find the best treatment for their condition sooner.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/metronorth.health.qld.gov.au\/extranet\/newsletters\/news-at-the-royal\/epilepsy-treatment\" \/>\n<meta property=\"og:site_name\" content=\"Staff Extranet\" \/>\n<meta property=\"article:published_time\" content=\"2022-05-31T05:30:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-27T06:23:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/metronorth.health.qld.gov.au\/staff-news\/wp-content\/uploads\/sites\/25\/2022\/05\/rbwh-lata-vadlamudi-b.jpg\" \/>\n<meta name=\"author\" content=\"nealeian\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/metronorth.health.qld.gov.au\/extranet\/newsletters\/news-at-the-royal\/epilepsy-treatment\",\"url\":\"https:\/\/metronorth.health.qld.gov.au\/extranet\/newsletters\/news-at-the-royal\/epilepsy-treatment\",\"name\":\"Mini-brains revolutionise epilepsy treatment - 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