Translational Research2021-12-08T12:28:10+10:00

Translational research

Genomic Institute Research 

The Genomic Institute is enabling translational genomics by providing a platform for the delivery of implementation focussed research outcomes.  The Genomic Institute research platform includes the provision of essential functions to facilitate research translation and mechanisms to support research development with clinical impact.

Enabling and advocating for research aligned with priority areas: Through consultation and continual engagement, the Genomic Institute is maintaining a research agenda that prioritises initiatives to ensure maximum impact and outcomes.  

Facilitation of partnerships: Partnerships capitalise on shared resources, enable funding and assist in predicting and minimising barriers to implementation. The Genomic Institute is  developing partnerships across a broad range of groups, to build on combined strengths for healthcare outcomes delivery. Partnerships across academic, health service, industry, research, patient and advocacy groups are priority, with the intent to enable leverage opportunities for mutual benefit.

Health service integration: The Genomic Institute represents a health service embedded facility by which to access health service expertise, data and clinical delivery. The Genomic Institute has developed pathways and service support expertise to enable efficient and informed process to access aspects of the health service, including methods to minimise barriers and to enable healthcare informed project design.

Supporting clinicians in research: Health practitioners and clinics inform health research with real impact. The Genomic Institute is supporting clinicians to undertake research in an approach that benefits clinical practice but also one that enables continuity of clinical care. By enabling partnerships and supporting clinically integrated practitioner led research functions, the Genomic Institute is enabling clinicians to inform or lead research, thereby maximising clinical input into research outcomes.

Provision of business support and governance: Research translation requires economic evaluation, governance, ethical review, process development and change management appropriate to the health service. Through demonstrator projects and heath service embedded expertise in service design and delivery, researchers and clinicians can access support for clinical development and change processes essential to deliver healthcare outcomes from research.

Supporting evaluation of outcomes: A learning healthcare system requires the continual integration of evidence into the health service. Health service change also requires early incorporation of evaluation measures, to inform and validate change processes and to clarify value of the outcomes. The Genomic Institute is supporting project and health service evaluation and analysis, to enable transition of research into service delivery.

Genomics training and student exchange opportunities: The Genomic Institute Learning Centre is supporting the integration of clinical students into research programs and supports embedding of research students into clinical facing projects. This provision of learning support also enables the change processes required for delivery of research outcomes into clinical care.

Genomic Institute Research Focus Areas

The Genomic Institute has developed a set of six broad areas which have been identified through extensive consultation as having the highest clinical relevance. The six focus areas represent priority areas to promote research translation with maximum impact. By supporting responsive and informed focus areas, the Genomic Institute will maintain responsive and current research with high impact outcomes that integrate patient needs and deliver real patient outcomes.

This will be delivered through six key research focus areas:

Rare and Monogenic Diseases

The Rare and Monogenic Diseases Program focuses on the diagnosis and treatment of rare and difficult to diagnose genetic disorders, to discover how genetic variants contribute to disease, with the ultimate goal of early curative treatment, optimised disease management and disease prevention.

Applied Computational Genomics and Technology

The Applied Computational Genomics and Technology Program will focus on the development and application of computationally intensive approaches to analyse large-scale genetic and genomic data and the translation of new technologies into practice, with a particular focus on identifying genetic contributions to human disease.

Functional Genomics

The Functional Genomics Program will study the complex relationship between genotype and phenotpe, and how genomic variation contributes to overall health.


The Complex Diseases Program studies the genomic and social determinants of complex diseases, including cardiovasular and renal disease, diabetes and obesity, by exploring the genetic, epigenetic and metagenomic basis of human disorders.


The Precision Health Research Program will develop and evaluate cutting edge genomic and informatic tools to improve the diagnosis, treatment, and prevention of disease to foster next-generation healthcare.

Ethical, Legal & Social Implications of Genomics

This Ethical, Legal and Social Implications (ELSI) of Genomics Program will focus on the ethical, legal and social implications of genomics research, including the following key issues: health disparities, genetic discrimination, human subjects research, informed consent, intellectual property, privacy and confidentiality, and regulation and economic implications. Of particular interest are studies that explore these issues with and within communities that have been underrepresented, underserved and/or mistreated in biomedical research and healthcare.

Partnerships, Collaborations and Sponsorships

The Genomic Institute is part of the Herston Health Precinct, a global leader in health, innovation, education, research, training and clinical care. The Institute supports local, national and international collaborative research and partnerships with health services, academic and research institutions, and commercial organisations.

Establishing strategic partnerships and research collaborations with organisations including Hospital and not-for-profit Foundations, Universities, Government and Industry is a key priority of the Genomic Institute.

For further information about how to get involved with research supported by the Genomic Institute, please email:    


Genomic Institute

Metro North Health
Block 7, Level 7
Royal Brisbane and Women’s Hospital

Phone: (07) 3646 1433

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