A/Prof Martin Batsone

The Maxillofacial Research Program at HBI, led by Associate Professor Martin Batstone, is advancing next-generation approaches to oral and craniofacial reconstruction through biofabrication, regenerative medicine and patient-centred research.

Building on internationally recognised expertise, the program is developing innovative technologies to improve functional outcomes and long-term patient recovery.

Key innovations include bioresorbable metal implants that eliminate the need for removal surgeries, and a patented magnetic retention system for facial prostheses, now translated into clinical use to reduce surgical burden and improve functional, aesthetic and psychosocial outcomes.

Underpinned by a strong patient-centred focus, the program integrates advanced scaffold design and regenerative strategies to support more biologically integrated tissue repair. Collectively, this work is establishing new clinical pathways aimed at reducing implant failure and enhancing long-term quality of life for patients with complex craniofacial conditions.

Note: The figure below relates to Professor Saso Ivanovski’s dental and maxillofacial program.

Modified from Han et al., Advanced Healthcare Materials, 2026, and Han et al., Biomaterials Advances, 2024, with permission.

Publications

• Abdal-hay A, Kocak-Oztug NA, Sheikh FA, et al. Fabrication of 3D bioactive melt electrowriting composite scaffold with high osteogenic potential. Colloids Surf B Biointerfaces 2025;245:114270.
• Staples R, Ivanovski S, Vaswani K, Vaquette C. Melt electrowriting scaffolds with fibre-guiding features for periodontal attachment. Acta Biomater 2024;180:337-57.
• Blaudez F, Ivanovski S, Vaquette C. Harnessing the Native Extracellular Matrix for Periodontal Regeneration Using a Melt Electrowritten Biphasic Scaffold. J Funct Biomater 2023;14.
• Blaudez F, Ivanovski S, Fernandez T, Vaquette C. Effect of In Vitro Culture Length on the Bone-Forming Capacity of Osteoblast-Derived Decellularized Extracellular Matrix Melt Electrowritten Scaffolds. Biomacromolecules 2023;24:3450-62.
• Farag A, Abdal-hay A, Han P, Ivanovski S. Fabrication of 3D melt electrowritting multiphasic scaffold with bioactive and osteoconductivite functionalities for periodontal regeneration. Ceram Int 2023;49:8015-21.
• Han P, Liu C, Jayasree A, et al. Nano-Engineered Titanium Implants Loaded With Gingival Fibroblasts-Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo. Advanced healthcare materials 2026:e04516.
• Han P, Dan H, Vaquette C, Liaw A, Zhou Y, Ivanovski S. Bioengineered mPCL scaffolds with LiCl-stimulated hPDLCs cell sheets for enhanced periodontal regeneration. Clin Oral Investig 2025;29:587.
• Han P, Raveendran N, Liu C, et al. 3D bioprinted small extracellular vesicles from periodontal cells enhance mesenchymal stromal cell function. Biomaterials Advances 2024;158:213770.
• Jiao K, Liu C, Basu S, et al. Bioprinting extracellular vesicles as a "cell-free" regenerative medicine approach. Extracell Vesicles Circ Nucl Acids 2023;4:218-39.
• Lam L, Ivanovski S, Lee RSB. Alveolar ridge preservation in posterior maxillary teeth for reduction in the potential need for sinus floor elevation procedures: A pilot study. Clin Oral Implants Res 2024;35:1568-84.
• Quach SS, Johnson N, Dudhia R, Puljich A, Ivanovski S, Lee RSB. The Periodontal Benefits of Alveolar Ridge Augmentation With Xenograft Following Third Molar Extraction: A Randomised Controlled Trial. J Clin Periodontol 2025;52:1419-29.
• Ivanovski S, Staples R, Arora H, Vaquette C, Alayan J. Alveolar bone regeneration using a 3D-printed patient-specific resorbable scaffold for dental implant placement: A case report. Clin Oral Implants Res 2024;35:1655-68.
• Mercado F, Vaquette C, Hamlet S, Ivanovski S. Enamel matrix derivative promotes new bone formation in xenograft assisted maxillary anterior ridge preservation-A randomized controlled clinical trial. Clin Oral Implants Res 2021;32:732-44.
• Mercado F, Hamlet S, Ivanovski S. Subepithelial connective tissue graft with or without enamel matrix derivative for the treatment of multiple Class III-IV recessions in lower anterior teeth: A 3-year randomized clinical trial. J Periodontol 2020;91:473-83.