A blood test could soon detect cervical cancer as RBWH and UQ launch CLARITY study

Cervical cancer may soon be able to be detected through a simple blood test, thanks to innovative new research out of Royal Brisbane and Women’s Hospital and University of Queensland.

RBWH Gynaecological Oncologist Professor Andreas Obermair, the chief investigator of the study at UQ’s Queensland Centre for Gynaecological Cancer Research, has embarked on the project to improve early detection and treatment options.

The study will investigate the potential of blood biomarkers in the screening, monitoring and management of cervical cancer.

“Despite advances in prevention and treatment, including the success of the Gardasil vaccine, cervical cancer continues to impose significant physical, emotional, and financial burdens on women worldwide,” Professor Obermair said.

“There are about 1000 women diagnosed with this cancer in Australia every year.

“There remains a critical need for more effective, non-invasive tools to support early detection, monitor treatment response, and guide clinical decision-making.’’

Professor Obermair said he hoped about 100 women would take part in the study over the next two years.

“The CLARITY study represents an important step towards developing less invasive diagnostic and monitoring tools for cervical cancer,’’ he said.

“A reliable, non-invasive test would also serve as a more accessible and acceptable alternative to current cervical screening methods, particularly for women who face cultural, systemic, or personal barriers.

“This is especially important for under-screened populations, including Aboriginal and Torres Strait Islander women and culturally diverse communities.’’

The CLARITY study will focus on preliminary comparative data on the diagnostic accuracy of blood biomarkers, providing a critical foundation for future large-scale investigations.

Cervical cancer often presents with no signs in its early stages, meaning regular cervical screening tests through a GP are essential. Cervical screening can by done by the GP or you may be eligible for a self-collected test at the GP clinic.

Common symptoms of cervical cancer, when they appear, include bleeding between periods, after sex and after menopause, pain in the pelvis as well as lower back or leg pain, swelling in legs, extreme fatigue and unintended weight loss.

Any woman experiencing symptoms should see their GP as soon as possible.