Caboolture Hospital

I’m having my 1st Telehealth appointment with a dietitian on the 18th !! Great timing Metro North.

There’s a familiar face from my nursing nursing prac out west about 17 years ago! Way to go Kate

If only they'd make mobile xray machines too or i would have

In neuro-biochemical textbooks, the agents responsible for the formation and growth of "internal scars" (tubers), nodules, and polyp-like cysts are primarily regulators of cell growth, signaling, and vascular permeability.Based on your descriptions of "scars," "polyp-like tumors," and "silica hair/lung-like" structures, the key biochemical agents involved are:1. mTOR (Mammalian Target of Rapamycin)This is the "master switch" for cell growth. In conditions like Tuberous Sclerosis Complex (TSC), mutations in the TSC1 (Hamartin) or TSC2 (Tuberin) genes prevent these proteins from inhibiting mTOR.Action: Unregulated mTOR leads to the creation of "giant cells" and disorganized tissue "scars" (tubers).Tumour Growth: It drives the transformation of small nodules (SENs) into polyp-like tumors called SEGAs.Treatment: Drugs like Everolimus are used as biochemical "inhibitors" to turn off this growth signal.2. VEGF (Vascular Endothelial Growth Factor)This is the biochemical agent likely responsible for your description of the "minute major capillary".Action: VEGF is an extremely potent inducer of angiogenesis (the formation of new blood vessels) and edemagenesis (the leaking of fluid that creates cysts).Tumor Effect: High levels of VEGF create the conspicuous, large-diameter capillaries often seen in polyp-like brain tumors like SEGAs.3. Shh (Sonic Hedgehog) and Wnt SignalingThese pathways are the biochemical drivers for structures that look like "hair" or "lung/throat" tissue inside the brain.Cilia Formation: These signals are transduced through primary cilia (tiny hairs on cells). If these pathways are active in the wrong place, they can lead to the growth of ciliated cysts (which look like the throat lining) or dermoid cysts (which contain actual hair follicles)."Silica Hair": In Dermoid Cysts, the biochemical environment allows for the production of keratin and sebum, which can crystallise and give hair a stiff, silica-like appearance.4. Aquaporin-4 (AQP4)This is a water-channel protein found in the "scars" and surrounding brain tissue.Action: It regulates the flow of fluid in and out of the brain's internal spaces.Cyst Formation: When AQP4 is dysregulated (often in the "scar" tissue or glia), it contributes to the buildup of fluid that forms internal brain cysts.Feature MentionedPrimary Biochemical AgentRelated ConditionInternal Scars / TubersmTOR Pathway (TSC1/TSC2)Tuberous SclerosisMinute Major CapillaryVEGF (Vascular Growth Factor)SEGA / GliomasLung/Throat/CiliaShh & Wnt SignalingCiliated / Colloid CystsSilica Hair / KeratinKeratinocyte Growth FactorsDermoid CystsWould you like to focus on the biochemical markers used to detect these agents in a lab setting, such as S6 kinase or GFAP?13 sitesThe neuronal cilium – a highly diverse and dynamic organelle ...15 May 2024 — Primary cilia serve as signaling hubs during neuronal development by transducing various signaling pathways, including Hedgehog, N...ScienceDirect.comPrimary Cilia in Brain Development and Diseases - ScienceDirect15 Jan 2018 — In the brain, primary cilia play critical roles at various stages of neurogenesis, from early patterning, through the proliferatio...ScienceDirect.comPrimary cilia in neural development and disease - ScienceDirectDuring neural tube development, Shh signaling is mediated by a cilium-localized Ptch1–Smo receptor complex, which regulates the ph...ScienceDirect.comShow all

Telehealths the best

Woohoo!! The best person for the job!!

Well done Lynette Smith!

🎊 congratulations Lynette!!!!!you are the definition of true all rounder! Lynette one of your biggest strengths is that you!!! Its very rare to find someone who can seamlessly fir into any role while remaining so humble and down to earth! So proud of u!!

Lynette is the most compassionate and caring person, but also a very high performer, she is so perfect for this position. Congratulations Lynette 👏 thank you for all your hard work, in every role you’ve done ❤️

This is wonderful Lynette. Well done!

Well done Lynnette 👏👏👏

Congratulations Lynette, always meant for great things xx

Great work Lynette could not think of a better person to hear at the other end of the phone. 🫶

Kicking goals!

Amazing at everything and so focused, well done Lynette Smith

Great job Lynette.

You are absolutely nailing it Lynette! Our patients are so lucky to have you. 🥰

You do a fabulous job Lynette CABH is lucky to have you 💖👩‍⚕️

So good Lynette!

The best voice to have at the other end of the phone for our patients! Wonderful Lynette ☺️

Doing an amazing job too Lynette, thank you.

Great Stuff #patientcentredcare ❤️

Amazing Lynette!

Sounds great, does Prince Charles have a similar service, i am going in for heart surgery soon.

I'm a CN with Caboolture PACS and would love to link in with you Lynette to ensure the best outcomes for our patients. I'll send you an email!

Georgina Sheridan

I kindly ask all my friends and loved ones to pray for my recovery. If anyone is able to offer financial help, please support me. Your prayers and your support mean a lot to me. Thank you for your kindness 🙏

I was discharged home from the PA's recovery room after surgery after they used two plates and screws to repair three fractures. I never saw the inside of a ward. When they sent me home they organised no home care for me and I live alone without support. As a former scrub nurse in an operating theatre it was the worse care I have ever seen of a surgical patient. Unlike the RBHWH which is very professional and caring. I think you guys should go to the PA and teach them about post operative care. Their CNC could learn a lot from you.