Dr Nicole Marsh
Nursing and Midwifery Director, Research
Dr Nicole Marsh’s research is focused on improving patient outcomes and decreasing complications associated with vascular access across the acute clinical care and community setting. Her PhD addressed risk factors for peripheral intravenous catheter failure in the adult population.
In addition, she has been a Clinical Trial Co-ordinator for more than 30 single and multi-centre clinical trials. She also has over 25 years’ experience in nursing with specialist qualifications in Neurosurgical Nursing.
In 2019 Dr Marsh was part of a team (CIC) awarded a NHMRC partnership grant: Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures.
- Dressings and securement
PISCES Trial: The study is a multi-centre, 2×2 factorial, superiority randomised controlled trial (RCT) to test (1) securements (Securement device vs. integrated securement device), and (2) dressings (chlorhexidine-disc vs. no disc) for peripherally inserted central catheters (PICCs) in Cancer patients. Principal Site Investigator: N Marsh
PICNIC trial: This study is a multicentre, parallel group, superiority RCT comparing the clinical- and cost- effectiveness of the (i) anti-thrombogenic (AT [Endexo®] and (ii) chlorhexidine gluconate PICCs, to (iii) conventional polyurethane PICCs in paediatric and adult patients. Principal Site Investigators: P, Harris, N Marsh
Midline trial: this RCT is comparing midline catheters and peripheral intravenous catheters (PVC) for the prevention of insertion failure and post-insertion failure; and to generate pilot data to support a larger, definitive trial. Principal Investigator: N Marsh
Optimum trial: A multi-centre RCT comparing an integrated PVC system against current practice a non-integrated system. Principal Site Investigator: N Marsh
Vascular Access Passport: this is a consumer-led innovation to implement improvements in central venous access device management in the cancer care population. Principal Site Investigators: E Larsen, N Marsh, N Roberts
Cocoa Trial: this RCT is comparing positive and neutral needleless connectors for the prevention of PVC failure. Principal Investigators: N Marsh, E Larsen, C O’Brien, Davies K, McLeod K, Booker C
Adorn trial: This RCT is comparing an anti-microbial disc to no-disc for infection prevention in central venous access devices in ICU. Principal Investigator: N Marsh
SURF Trial: This study aims to test the feasibility of evaluating perforated versus non-perforated peripheral catheter design. Cancer care patients requiring injection of contrast via PIVC for a Computerised Tomography (CT) scan for diagnosis or staging of malignant oncology or haematology conditions, will be enrolled.
- Finalist – Rising Star Award. 2020 Metro North Research Excellence Awards. Marsh N.
- Menzies Health institute Queensland, Excellence in Publication Award. Griffith University. Alliance for vascular access for observational study of peripheral intravenous catheter outcomes in adult hospitalized patients: A multivariable analysis of peripheral intravenous catheter failure. Marsh N.
- Vice Chancellor’s Research Excellence Award – Research Group or Team. Rickard C, Cooke M, Byrnes J, Bulmer A, Ullman A, Ray-Barruel, Marsh N, Schults J, Kleidon T
- Health Service and Implementation Research Award, Metro North 2019 Research Excellence Awards. Marsh N, Webster J, Rickard C, Larsen E, August D, Flynn J, Corley A
- Best Paper Prize, Australian Vascular Access Society (AVAS) Scientific Meeting, Sydney 2019. Marsh N, Webster J, Larsen E, Genzel J, Cooke M, Mihala G, Rickard C
- Service Line Award (Quarrie Award), Quality Awards Recognising Remarkable Initiative and Excellence in Service. Royal Brisbane and Women’s Hospital. Understanding vascular access outcomes at the RBWH, 2019. Marsh N, Webster J, Larsen E, Groom P, Tapp S, Nicholas M
- Cecilia Brazil Nursing Research Award. 27th Annual Royal Brisbane and Women’s Hospital Healthcare Symposium. Peripheral intravenous catheter failure and complications within the adult population: a systematic review, 2018. Marsh N, Webster J, Ullman A, Mihala G, Cooke M, Rickard CM.
- Menzies Health institute Queensland, Excellence in Publication Award. Griffith University. Devices and dressings to secure peripheral venous catheters: A Cochrane systemic review and meta-analysis. 2018. Marsh N, Webster J, Mihala G, Rickard CM.
- Pro Vice Chancellor Health Research Excellence Award – Research Team Award. Griffith University, 2018. Rickard C, Cooke M, Byrnes J, Bulmer A, Ullman A, Ray-Barruel, Marsh N, Schults J, Kleidon T
- Service Line Award (Quarrie Award), Quality Awards Recognising Remarkable Initiative and Excellence in Service. Royal Brisbane and Women’s Hospital. Advancement in RBWH Nursing Research. Nursing and Midwifery Research Centre. (for “Advancement of RBWH Nursing Research”), 2018. Webster J, Marsh N.
- Teacher of the year. Alliance for Vascular Access Teaching and Research (AVATAR) Griffith University, Brisbane, Australia. 2019. Marsh N.
- Gavin CN, Kleidon T, Larsen E, O’Brien C, Ullman A, Northfield S, Mihala G, Runnegar, Marsh N, Rickard CM. A comparison of hydrophobic polyurethane and polyurethane peripherally inserted central catheter: results from a feasibility randomized controlled trial. 2020; 21(787): 1-11 https://doi.org/10.1186/s13063-020-04699-z
- Schults J, Kleidon T, Chorpa V, Cooke M, Moore R, Ullman A, Marsh N, Ray-Barruel G, Hill J, Devrim I, Hammarskjöld F, Pedreira M, Bertoglio S, Egan G, Mimoz O, Van Boxtel T, DeVries C, Magalhaes M, Hallam C, Oakley S, Rickard CM. International recommendations for a vascular access minimum data set: A Delphi consensus-building study. BMJ Quality and Safety. 2020; 0: 1-9 http://doi.org/10.1136/bmjqs-2020-011274
- Massey D, Ray-Barruel G, Cooke M, Ullman A, Wallis M, Marsh N, Craswell A. (2020) Undergraduate nursing students’ perceptions of the current content and pedagogical approaches used in PIVC education. A qualitative descriptive study. Nurse Education Today. https://doi.org/10.1016/j.nedt.2020.104577
- Kleidon T, Horowitz J, Rickard CM, Ullman A, Marsh N, Schults J, Ratz D, Chopra V. (2020) Peripherally Inserted Central Catheter Thrombosis Following placement via electrocardiography vs. traditional methods: an analysis of 42,687 patients. American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2020.06.010
- Larsen E, Marsh N, O’Brien C, Monteagel E, Friese C, Rickard CM. Inherent and modifiable risk factors for peripheral venous catheter failure during cancer treatment: a prospective cohort study. Supportive Care in Cancer. https://doi.org/10.1007/s00520-020-05643-2
- Larsen EM, Corley A, Mitchell M, Lye I Powell M, Tom S, Mihala G, Ullman AJ, Gibson V, Marsh N, Kleidon TM, Rapchuk IL, Rickard CM. A pilot randomised controlled trial of two dressing and securement methods to prevent arterial catheter failure in intensive care. Australian Critical Care. http://doi.org/10.1016/j.aucc.2020.05.004
- Larsen E, Byrnes J, Marsh N, Rickard CM. (2020). Patient reported outcome and experience measures for peripheral venous catheters: a scoping review protocol. Vascular Access. 14 (1), 6-11.
- Marsh N, Larsen E, Webster J, Cooke M, Rickard CM. The benefit of a vascular access specialist placing a peripheral intravenous catheter: a narrative review of the literature. (2020). Vascular Access.; 6(1):10-15. DOI: 33235/va.6.1.10-15
- Marsh N, Larsen E, Flynn, J, O’Brien, Kleidon T, Groom P, Hewer B, Rickard CM. The MIDLINE trial – Managing intravenous devices among patients with limited vascular access or prolonged therapy: a pilot randomised control trial protocol. (2020) Vascular Access. 6(1):10-15. DOI: 33235/va.6.1.20-24
- Kleidon T, Rickard C, Gibson V, Mihala G, Schults J, Xu G, Bauer M, Marsh N, Larsen E, Cattanach P, Ullman A. (2020) A pilot randomized controlled trial of peripheral intravenous catheter securement in pediatrics. Journal of Tissue Viability. JIF=5.5 DOI: 1016/j.jtv.2020.03.006
- Ray-Barruel G, Wu M, Marsh N, Mitchell B. (2020). Strategies for CAUTI prevention: Are we on the same page? (letter to the Editor) Infection, Disease and Health.
- Schults J, Woods C, Cooke M, Kleidon T, Marsh N, Ray-Barruel G, Rickard CM. (2020). Healthcare practitioner perspectives and experiences regarding vascular access device data: An exploratory study. International Journal of Healthcare Management. DOI: 1080/20479700.2020.1721750
- Corley, A, Ullman AJ, Marsh N, Larsen EN, Mihala G, Harries P, Rickard CM. (2019) SECUREment bundles to prevent Peripheral Intravenous Catheter failure: the SECURE-PIVC trial. Study protocol for a pilot randomized controlled trial. Canadian Vascular Access Association Journal.; 13(3), 6-14. JIF-N/A.
- Lye I, Corley A, Rickard CM, Marsh N. (2019). Removal versus retention of vascular access devices (VADs) suspected of infection in the intensive care unit (ICU): a narrative review of the literature. Vascular Access. 2019; 5(2):42-48. DOI: 10.33235/va.5.2.42-48
- Marsh N, Larsen E, Tapp S, Sommerville M, Mihala G, Rickard CM. (2019). Management of Hospital In The Home (HITH) Peripherally Inserted Central Catheters: a retrospective cohort study. Home Health Care Management & Practice. DOI: 10.1177/10848223198733
- Larsen EN, Gavin N, Marsh N, Rickard CM, Runnegar N, Webster J. (2019) A systematic review of central-line-associated bloodstream infection (CLABSI) diagnostic reliability and error. Infection Control & Hospital Epidemiology, 1-7. DOI: 1017/ice.2019.205. JIF=3.084
- Ray-Barruel G, Woods C, Larsen E, Marsh N, Ullman A, Rickard CM. (2019) Nurses’ decision-making about intravenous administration set replacement: a qualitative study. Journal of Clinical Nursing. DOI: 10.1016/j.idh.2019.03.001. JIF=1.635
- Choudhury, M.A, Sidjabat, H., Zowawi, H., Marsh, N., Larsen, E., Runnegar, N., Paterson, D., McMillan, D., & Rickard, C. (2019). Skin colonisation at peripheral intravenous catheter insertion sites increases the risk of catheter colonisation and infection. American Journal of Infection Control. DOI: 10.1016/j.ajic.2019.06.002. JIF=1.929
- Ullman AJ, Keidon TM, Turner K, Gibson V, Dean A, Cattanach P, Pitt C, Woosley J, Marsh N, Gavin N, Takashima M, Rickard CM. (2019). Skin complications associated with paediatric central venous access devices: Prevalence, incidence and risk. Journal of Pediatric Oncology Nursing. DOI: 10.1177/1043454219849572. JIF=1.295
- Ray-Barruel G, Xu H, Marsh N, Cooke M, Rickard CM. (2019). Effectiveness of insertion and maintenance bundles in preventing peripheral intravenous catheter-related complications and bloodstream infection in hospital patients: a systematic review. Infection, Disease & Health. DOI: 10.1177/1043454219849572. JIF=N/A
- Webster J, Ray-Barruel G, Rickard CM, Marsh N, Mihala G, Alexandrou E. (2019) “Just in case”. Use of large bore peripheral intravenous catheters in parturient women: a global study. Vascular Access. 5(1). JIF=N/A
- Webster J, Osborne S, Rickard CM, Marsh N. (2019) Clinically-indicated replacement versus routine replacement of peripheral venous catheters. Cochrane Database of Systematic Reviews 2019, Issue 1. Art. No.: CD007798. DOI: 10.1002/14651858.CD007798.pub5. JIF=6.174
- Ullman AJ, Mihala G, O’Leary K, Marsh N, Woods C, Bugden S, Scott M, Rickard CM. Skin Complications associated with vascular access devices: A secondary analysis of 13 studies involving 10,859 devices. (2019). International Journal of Nursing Studies. 91, 6-13. DOI: 10.1016/j.ijnurstu.2018.10.006. JIF=3.654
- Moureau N, Marsh N, Zhang L, Bauer MJ, Larsen E, Mihala G, Corley A, Lye I, Cooke M, Rickard CM. (2018). Evaluation of Skin Colonisation And Placement of vascular access device Exit sites (ESCAPE Study). Journal of Infection Prevention. DOI: 10.1177/1757177418805836. JIF=N/A
- Marsh N, Larsen E, Genzel J, Mihala G, Ullman A, Kleidon T, Cadigan S, Rickard CM. (2018). A novel integrated dressing to secure peripheral intravenous catheters in an adult acute hospital: a pilot randomised controlled trial. Trial 19:596. DOI: 10.1186/s13063-018-2985-9. JIF=2.067
- Marsh N, Webster J, Larsen E, Genzel J, Cooke M, Mihala G, Cadigan S, Rickard CM. (2018). Expert versus generalist peripheral intravenous catheter insertion: A pilot randomised controlled. 19:564. DOI: 10.1186/s13063-018-2946-3. JIF=2.067
- Webster J, Laws J, Larsen E, Booker C, Marsh,N. (2018). Prophylactic insertion of large bore peripheral intravenous catheters in maternity patients: A cohort study. ANZ journal of Obstetrics and Gynaecology. 58, 548-552. DOI: 10.1111/ajo.12759. JIF=7.733
- Tuffaha H, Marsh N, Byrnes J, Gavin N, Webster J, Cooke M, Rickard CM. (2018)The economic burden of vascular access devices in public hospitals in Queensland. Australian Health Review. DOI: 1071/AH18102. JIF=1.036
- Rickard CM, Marsh N, Webster J, Runnegar N, Larsen E, McGrail MR, Fullerton F, Bettington E, Whitty JA, Choudhury MA, Tuffaha H, Corley A, McMillan DJ, Fraser JF, Marshall AP, Playford EG. (2018). Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial. 392(10145), 419-430. IF 53.254
- Mihala G, Ray-Barruel G, McGrail M, Marsh N, Webster J, Wallis M, Chopra V, Rickard CM. (2018) Phlebitis signs and symptoms in peripheral intravenous catheters: incidence and correlation study. Journal of Infusion Nursing. 41(4). DOI: 10.1097/NAN.0000000000000288. IF 0.67
- Woods C, Keogh S, Flynn J, Marsh N, Larsen E, Rickard CM. (2018). Nurses’ and stakeholder perceptions of improving peripheral intravenous catheter dressing and securement. Vascular Access. 2018; 4(1): 1-9. IF N/A
- Castillo MI, Larsen E, Cooke M, Marsh N, Wallis M, Finucane J, Brown P, Mihala G, Carr P, Byrnes J, Walker R, Cable P, Zhang L, Sear C, Jackson G, Rowsome A, Ryan A, Humphries JC, Sivyer S, Flanigan K, Rickard CM. (2018). Integrated versus non-integrated peripheral intravenous catheter. Which is the most effective system for peripheral intravenous catheter management? (The OPTIMUM study): A randomised controlled trial protocol. BMJ Open. DOI:10.1136/bmjopen-2017-019916. IF=2.413
- Marsh N, Webster J, Larsen E, Cooke M, Mihala G, Rickard CM. (2018). Observational study of peripheral intravenous catheter outcomes in adult hospitalised patients – a multivariable analysis of peripheral catheter failure. Journal of Hospital Medicine. 13(2):83-89. IF=2.331