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Ms Emily N Larsen2020-08-20T10:01:17+10:00

Project Description

Ms Emily N Larsen

Emily Larsen is a Research Fellow, Vascular Access, with a joint position between the Royal Brisbane and Women’s Hospital, and Griffith University. As a clinician and emerging researcher, Emily is demonstrating a strong research trajectory, publishing 30 peer-reviewed journal articles (9 H index, 253 citations, Google Scholar), receiving approximately $750, 000 in competitive research grants, winning seven awards and speaking at eight conferences, in the last 5 years. Ms Larsen current research focus explores the role, and development of Patient Reported Outcome and Experience Measures for peripheral intravenous catheters. Since 2014, Ms Larsen has been a Project Manager for over 20 single and multi-centre clinical trials, cohort studies and qualitative inquiries, including the National Health and Medical Research Council funded multi-centre randomised controlled trial ‘PISCES Trial’ (comparing four dressing and securement methods for Peripherally Inserted Central Catheters). Ms Larsen’s interests and expertise include: the patient’s experience of IV access; vascular access devices in Cancer Care; and the classification, and prevention of, catheter-associated bloodstream infections.

  • Vascular Access
  • Randomised Controlled Trials
  • Qualitative Research

Clinical Trials (last 5 years)

  • PISCES Trial (Peripherally InSerted CEntral catheter dressing and Securement)
  • OPTIMUM Trial (Integrated versus nOn-integrated Peripheral inTravenous catheter. Which Is the most clinical and cost-effective systeM for peripheral intravenoUs catheter Management?)
  • Peripheral IntraVenous catheter (PIV) Awareness Study
  • CVAD PROM PREM Project (Measuring Quality of Life and Experience for Central Venous Access Devices in Cancer Care: Developing and preliminary testing of MyVAD)
  • ADORN Trial (AMD Disc infectiOn pReventioN in vascular access)
  • PIV-COCOA Trial: Controlling device Occlusion by needleless ConnectOr design. A pilot randomised control trial
  • DIAMETER Study (Developing Ideal catheter to vein ratio parameters for peripheral venous And Midline devices: recommendations to prevent catheter failure)
  • COMPACT Trial (COmparing the use of Midline Catheters versus Peripherally Inserted Central CAtheters for patients requiring peripherally Compatible Therapies: A randomised controlled trial)
  • Vascular Access PASSPORT Study (Consumer-led innovation to implement improvements in vascular access device management)

  • 2019 – Winner, Health Services and Implementation Research Award. 2019 Research Excellence Awards – Metro North Hospital and Health Service. Marsh N, Webster J, Rickard CM, Larsen E, August D, Flynn J, & Corley A.
    Improving vascular access outcomes among patients admitted to hospital, while minimising economic inefficiencies.
  • 2019 – (Co-Author) Winner, Menzies Health Institute Queensland Publication Quality Scheme. Healthcare Practice and Survivorship Category. Ref. Marsh, N., Webster, J., Larsen, E., Cooke, M., Mihala, G., & Rickard, C. (2018). Observational study of peripheral intravenous catheter outcomes in adult hospitalised patients – a multivariable analysis of peripheral intravenous catheter failure.
    Journal of Hospital Medicine, 13(2), E1-E7.
  • 2019 – Service Line Award (Nursing and Midwifery Services). 2019 QuARRIES, Royal Brisbane and Women’s Hospital. Marsh N, Webster J, Larsen E, Groom P, Tapp S, Nicholas M, Rickard C.
    Understanding vascular access outcomes within RBWH.
  • 2019 – Best Paper. The Australian Vascular Access Society 3rd Scientific Meeting. Marsh N, Webster J, Larsen E, Genzel J, Cooke M, Mihala G, Rickard, C. 2019.
    A pilot randomised controlled trial of two insertion models (expert versus generalist).
  • 2018 – Service Line Award (Nursing and Midwifery Services). 2018 QuARRIES Awards, Royal Brisbane and Women’s Hospital.
    Advancement of RBWH Nursing Research.
  • 2017 – Best Safety and Quality Paper. ANZICS/ACCCN Intensive Care Annual Scientific Meeting (ASM) (Gold Coat, Australia). Rickard C, Marsh N, Larsen E, Corley A, Spooner A, Fraser J, Davis C, Lepelaar S, Long D, Roberts B, Baker S, Gill F, Gowardman J, Murgo M, Alexandrou E, Palermo A, Regli A, McGrail M, & Runnegar N. 2017.
    Intravenous administration set (infusion tubing) replacement every 4 or 7 days is equally effective to prevent bloodstream infections (RSVP Trial).
  • 2017 – Clinical Research Award. The 26th annual Royal Brisbane and Women’s Hospital Healthcare Symposium. Rickard C, Webster J, Marsh N, Larsen E (Presenter), Gavin N, McGrail M, Runnegar N, Playford G, Reynolds H, Gowardman J. 2017.
    Intravenous administration set (infusion tubing) replacement after 4 or 7 days is equally effective to prevent bloodstream infections (RSVP trial).
  • 2017 – Best Paper. The Australian Vascular Access Society 2nd Scientific Meeting. Larsen E. (Presenter) Keogh, S., Marsh, N., Rickard, C. 2017.
    What is the patient’s experience of peripheral venous catheter insertion?
  • 2016 – Highly Commended.  2016 Research Excellence Awards – Metro North Hospital and Health Service. Webster J, Rickard CM, Marsh N, Gavin N, Larsen E, Keogh S.
    Improving IV outcomes for acute care patients.

Publications

  1. Larsen, E., Corley, A., Mitchell, M., Lye, I., Powell, M., Tom, S., Mihala, G., Ullman, A., Gibson, V., Marsh N., Kleidon, T., Rapchuk, I., & Rickard C. A pilot randomised controlled trial of two dressing and securement methods to prevent arterial catheter failure in anaesthetic and intensive care units. Australian Critical Care, (accepted).
  2. Larsen, E., Byrnes, J., Marsh, N., & Rickard, C. (2020). Patient reported outcome and experience measures for peripheral venous catheters: a scoping review protocol. Vascular Access, (accepted).
  3. Marsh, N., Larsen, E., Webster, J., Cooke, M., Rickard, C. (2020). The benefit of a vascular access specialist placing a peripheral intravenous catheter: a narrative review of the literature. Vascular Access, (accepted).
  4. Marsh, N., Larsen, E., Flynn, J., Obrien., C., Kleidon, T., Groom, P., Hewer, B., Rickard, C. (2020). The MIDLINE Trial – Managing intravenous devices among patients with limited vascular access or prolonged therapy: a pilot randomised control trial protocol. Vascular Access, (accepted).
  5. Corley, A., Ullman, A., Marsh, N., Larsen, E., Mihala G., Harris, P., & Rickard, C. (2019). SECUREment bundles to prevent Peripheral IntraVenous Catheter failure: the SECURE-PIVC trial. Study protocol for a pilot randomised controlled trial. Vascular Access (e-pub ahead of print).
  6. Kleidon, T., Rickard, C., Gibson V., Mihala, G., Schults, J., Xu, H., Bauer, M., Marsh, N., Larsen, E., Cattanach, P., & Ullman, A. (2020). A pilot randomised controlled trial of peripheral intravenous catheter securement in paediatrics. Journal of Tissue Viability, 29(2), 82-90. https://doi.org/10.1016/j.jtv.2020.03.006 (IF: 2.831; Citations: 0)
  7. Larsen, E., Gavin, N., Marsh, N., Rickard, C., Runnegar, N., & Webster, J. (2019). A Systematic Review of Central Line-Associated Bloodstream Infection (CLABSI) Diagnostic Reliability and Error. Infection Control and Hospital Epidemiology, 40(10), 1100-1106. https://doi.org/10.1017/ice.2019.205 (IF: 3.084; Citations: 0)
  8. Marsh, N., Larsen, E., Tap, S., Sommerville, M., Mihala, G., & Rickard, C. (2019). Hospital in the Home (HITH) Management of Peripherally Inserted Central Catheters – a retrospective cohort study. Home Healthcare Management and Practice, 32(1), 34-39. https://doi.org/10.1177/1084822319873334 (IF: 0.760; Citations: 0)
  9. Flynn, J., Larsen, E., Keogh, S., Ullman, A., & Rickard, C. (2019). Response to Letter to the Editor: Methods for microbial needleless connector decontamination: A systematic review and meta-analysis. American Journal of Infection Control, (e-pub ahead of print). (IF: 1.929; Citations: 0)
  10. Keogh, S., Mathew, S., Alexandrou, E., Bulmer, A., Cooke, M., Coventry, L., Hawthorn, A., Kleidon, T., Larsen, E., Marsh, N., Marshall, A., Ray-Barruel, G, Sinclair, S., Slaughter, E., St John, A., Taliaferro, K, Ullman, A., & Rickard, C. (2019). Peripheral intravenous catheters: A review of guidelines and research. Australian Commission on Safety and Quality in Health Care, Sydney.
  11. Choudhury, M.A, Sidjabat, H., Zowawi, H., Marsh, N., Larsen, E., Runnegar, N., Paterson, D., McMillan, D., & Rickard, C. (2019). Skin colonisation at peripheral intravenous catheter insertion sites increases the risk of catheter colonisation and infection. American Journal of Infection Control, 47(12), 1484-1488. https://doi.org/10.1016/j.ajic.2019.06.002 (IF: 1.929; Citations: 0)
  12. Ray-Barruel, G., Woods, C., Larsen, E.N., Marsh, N., Ullman, A.J., & Rickard, C. (2019). Nurses’ perceptions and decision making about intravascular administration set replacement: a qualitative study. Journal of Clinical Nursing, 28, 3786-3795. https://doi.org/10.1111/jocn.14979 (IF: 1.757; Citations: 0)
  13. Flynn, J., Larsen, E., Keogh, S., Ullman, A., & Rickard, C. (2019). Methods for microbial needleless connector decontamination: A systematic review and meta-analysis. American Journal of Infection Control, 47(8), 956-962. https://doi.org/10.1016/j.ajic.2019.01.002 (IF: 1.929; Citations: 7)
  14. Rickard, C., Marsh, N., Webster, J., Runnegar, N., Larsen, E., McGrail, M., Fullerton, F., Bettington, E., Whitty, JA., Choudhury, M., Tuffaha, H., Corley, A., McMillan, D., Fraser, J., Marshall, A., & Playford, G. (2018). Dressings and securements for the prevention of peripheral intravenous catheter failure (SAVE Trial) in adults: a pragmatic, randomised, controlled, superiority trial. The Lancet, 392(10145), 419-430. https://doi.org/10.1016/S0140-6736(18)31380-1 (IF: 59.102; Citations: 28)
  15. Marsh, N., Webster, J., Larsen, E., Genzel, J., Cooke, M., Mihala, G., Cadigan, S., & Rickard, C. (2018). Expert versus generalist peripheral intravenous catheter insertion: a pilot randomised controlled trial (The RELIABLE Trial). Trials, 19(1), 564. https://doi.org/10.1186/s13063-018-2946-3 (IF: 2.257; Citations: 7)
  16. Marsh, N., Larsen, E., Genzel, J., Mihala, G., Ullman, A., Kleidon, T., Cadigan, S., & Rickard, C. (2018). A novel integrated dressing to secure peripheral intravenous catheters in an adult acute hospital: a pilot randomised controlled trial. Trials, 19(1), 596. https://doi.org/10.1186/s13063-018-2985-9 (IF: 2.257; Citations: 6)
  17. Moureau, N., Marsh, N., Zhang, L., Bauer, M., Larsen, E., Mihala, G., Corley, A., Lye, I., Cooke, M., & Rickard, C. (2018). Evaluation of Skin Colonisation And Placement of vascular access device Exit sites (ESCAPE Study). Journal of Infection Prevention, 20(1), 51-59. https://doi.org/10.1177/1757177418805836 (IF: 0.960; Citations: 3)
  18. Woods, C., Ray-Burruel, G., Marsh, N., Flynn, J., Larsen, E., & Rickard, C. (2018). Registered Nurses’ experiences of using four methods of peripheral intravenous catheter dressings and securement during a randomised controlled trial. A Survey. Vascular Access, 4(1).
  19. Takashima, M., Gavin, N., Larsen, E., Northfield, S., Mihala, G., Corley, A., Ziegenfuss, M., & Rickard, C. (2018). Building a central vascular access device registry in an adult intensive care unit: feasibility study. Vascular Access, 4(1).
  20. Webster, J., Northfield, S., Larsen E., Marsh N., & Rickard, C. (2018). Insertion site assessment of peripherally inserted central catheters: Inter-observer agreement between nurses and patients. Journal of Vascular Access, 19(4), 370-374. https://doi.org/10.1177/1129729818757965 (IF: 1.397; Citations: 2)
  21. Marsh, N., Webster, J., Larsen, E., Cooke, M., Mihala, G., & Rickard, C. (2018). Observational study of peripheral intravenous catheter outcomes in adult hospitalised patients – a multivariable analysis of peripheral intravenous catheter failure. Journal of Hospital Medicine, 13(2), E1-E7. http://dx.doi.org/12788/jhm.2867(IF: 2.143; Citations: 45)
  22. Castillo, M., Larsen, E., Cooke, M., Marsh, N., Wallis, M., Finucane, J., Brown, P., Mihala, G., Carr, P., Byrnes, J., Walker, R., Cable, A., Zhang, L., Sear, C., Jackson, G., Rowsome, A., Ryan, A., Genzel, J., Humphries, J., Celenza, T., Sivyer, S., Flanigan, K., & Rickard, C. (2018). Integrated versus nOn-integrated Peripheral inTravenous catheter. Which Is the most clinical and cost-effective systeM for peripheral intravenoUs catheter Management? (The OPTIMUM study): A randomised controlled trial protocol. BMJ Open, 8(5), e019916. http://dx.doi.org/10.1136/bmjopen-2017-019916 (IF: 2.376; Citations: 4)
  23. Webster, J., Larsen, E., Marsh, N., Booker, C., & Laws, J. (2018). Prophylactic insertion of large bore peripheral intravenous catheters in maternity patients for postpartum haemorrhage: A cohort study. The Australian and New Zealand Journal of Obstetrics and Gynaecology, 58(5), 548-552. https://doi.org/10.1111/ajo.12759 (IF: 1.455; Citations: 5)
  24. Webster, J., Larsen, E., Marsh, N., Choudhury, M., Harris, P., & Rickard, C. (2017). Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of Central-Line-Associated Blood Stream Infection: a feasibility randomised controlled trial (the CLABSI trial). Journal of Hospital Infection, 96(3), 223-228. https://doi.org/10.1016/j.jhin.2017.04.009 (IF: 3.354; Citations: 13)
  25. Rickard, C. M, Marsh, N., Webster, J., Gavin, N., Chan, R., McCarthy, A., Mollee, P., Ullman, A., Kleidon, T., Chopra, V., Zhang, L., McGrail, M., Larsen, E., Choudhury, M., Keogh, S., Alexandrou, E., McMillan, D., Mervin, M. C., Paterson, D., Cooke, M., Barruel, G. , Castillo, M., Hallahan, A., Corley, A., Playford, G. (2017). Peripherally InSerted CEntral catheter dressing and Securement in cancer patients: the PISCES Trial. Protocol for a 2×2 factorial, superiority randomised controlled trial. BMJ Open, 7(6), e015291. https://doi.org/10.1136/bmjopen-2016-015291 (IF: 2.376; Citations: 8)
  26. Larsen, E., Keogh, S., Marsh, N., & Rickard, C. (2017). Adult medical and surgical patients’ experiences of peripheral IV insertion in hospital: A qualitative study. British Journal of Nursing (IV Therapy Supplement), 26(19). https://doi.org/10.12968/bjon.2017.26.19.S18 (IF: 0.46; Citations: 19)
  27. Chan, R., Northfield, S., Larsen, E., Mihala, G., Ullman, A, Hancock, P., Marsh, N., Gavin, N., Wyld, D., Allworth, A., Russell, E., Choudhury, M., Flynn, J., & Rickard, C. (2017). Central venous Access device SeCurement And Dressing Effectiveness for peripherally inserted central catheters in adult acute hospital patients (CASCADE): A Pilot Randomized Controlled Trial. Trials, 18(1), 458. https://doi.org/10.1186/s13063-017-2207-x (IF: 2.257; Citations: 17)
  28. Zhang, L., Cau, S., Marsh, N., Ray-Burruel, G., Flynn, J., Larsen, E., & Rickard, C. (2016). Infection risks associated with peripheral vascular catheters. Journal of Infection Prevention, 17(5), 207-213. https://doi.org/10.1177/1757177416655472 (IF: 0.960; Citations: 40)

Email: Emily.larsen@health.qld.gov.au

Phone: (07) 3646 8740

Unavailable from November 2020 to August 2021.  Off-site Fridays (Griffith University or WFH during COVID19)

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