Queensland Renal Genetics Clinic

The Queensland Renal Genetics Clinic is a collaborative clinical service of the Royal Brisbane and Women’s Hospital, Townsville University Hospital, and the Queensland Children’s Hospital. The clinic is hosted by Genetic Health Queensland, and is a statewide clinical service accepting referrals from across Queensland.

The adult clinic is based at the Royal Brisbane and Women’s Hospital and Townsville University Hospital, and the paediatric clinic is based at the Queensland Children’s Hospital, however regional telehealth clinics are also performed. The clinics are conducted using a multidisciplinary approach with both nephrology and genetics staff in attendance.

Individuals who might be referred to the Queensland Renal Genetics Clinics include children/adults with a confirmed or suspected diagnosis/family history of:

• Alport syndrome (AS)
• Thin basement membrane nephropathy (TBMN)
• Nephrotic syndrome (NS)
• Focal segmental glomerulosclerosis (FSGS)
• Kidney cysts
• Autosomal dominant polycystic kidney disease (ADPKD)
• Autosomal recessive polycystic kidney disease (ARPKD)
• Nephronophthisis
• Renal cysts and diabetes syndrome (RCAD)
• Medullary cystic kidney disease (MCKD)
• Tubulointerstitial kidney disease (TKD)
• Atypical haemolytic uraemic syndrome (aHUS)
• Tubulopathies
• Unknown chronic renal failure

For specialist advice, email Renal Genetics MDT at Renal_genetics_MDT@health.qld.gov.au.

Genetic Kidney Disease Decision Aids

The Genetic Kidney Disease (GKD) Decision Aids are a suite of decision support tools to guide and enable adoption of genomic testing as a diagnostic tool in renal services in Queensland.

Developed by a collaboration between the clinical experts in the Queensland Renal Genetics service and the Clinical Skills Development Service, and reviewed by naïve and expert users.

Topics include:

• identification of patients with GKD
• key clinical diagnostic features for different GKD subtypes
• selection of appropriate genomic test panels
• processes for requesting tests, and
• result interpretation.

They do not represent specific clinical direction for any individual clinical scenario or patient.  Users outside of Queensland should clarify clinical practices and genomic testing processes for their location.

Decision Aids

• How to use the decision aids
• Cystic diseases
• Tubulointerstitial diseases
• Glomerular diseases
• Tubulopathies
• Complement diseases
• Congenital anomalies of the kidney and urinary tract (CAKUT)
• Requesting genomic test
• Interpreting results

CC BY-NC-SA: This license allows reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator. If you remix, adapt, or build upon the material, you must license the modified material under identical terms.