Journal articles

CONCLUSIONS: Left ventricular unloading was not associated with improved survival in the context of ECPR and may increase complication rates. Randomised data are required to confirm these findings.

CONCLUSION: The newly developed outcome measure will require further testing to determine psychometric properties.

Vancomycin is an important antimicrobial for prophylactic, empirical and directed therapy of Gram-positive organisms. Therapeutic drug monitoring is recommended for all patients expected to receive vancomycin for more than 48 hours to optimise drug exposure. Monitoring the area under the concentration-time curve over a 24-hour period (AUC(24)) for vancomycin is preferred over monitoring trough plasma […]

CONCLUSION: Use of a bottom-up methodology allows calculation of staffing to meet best practice. Proposed dietetic staffing levels obtained from this study are far greater than current allocated staffing within the Australian adult CIF setting. Adequate dietetic resourcing may reduce patient complications and improve quality of life, resulting in enhanced patient and clinical outcomes.

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For many authors, the publishing world is opaque and complex. With the rise of predatory journals, the sharks are circling inexperienced authors. There have been steps taken by publishers to mitigate the risk to scientific publishing, and this article seeks to approach the issue from the author's view.

PURPOSE OF REVIEW: To examine the evidence and continuing role of strategies for the primary prevention and treatment of obesity in the context of effective obesity pharmacotherapies, through a narrative review.

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CONCLUSIONS: These findings underscore the value of species-level identification in managing CoNS BSIs, particularly in cases with clinical signs and symptoms, to support antimicrobial stewardship.

Surgical aortic valve replacement (AVR) is the standard of care for severe aortic valve disease; however, post-operative complications continue to pose challenges. Inflammation caused by increased release of cell-free mitochondrial DNA (cf-mtDNA) during surgery may be a contributing factor. The aim of this pilot study was to investigate the relationship between cf-mtDNA release and the […]

We investigated the pharmacokinetics (PK) of intravenous fosfomycin in critically ill patients undergoing different types of kidney replacement therapy (KRT) to identify optimized dosing regimens for patient care. Four prospective, observational studies contributed data of critically ill patients with prolonged-intermittent KRT (PIKRT, n=18), continuous KRT (CKRT, n=15), or without KRT (n=12) for population PK analysis. […]

Atrial fibrillation (AF) is the most common arrhythmia experienced by critically ill patients. It has been associated with adverse short-and long-term outcomes, including an increased risk of thromboembolic events, heart failure, and death. Due to complex and multifactorial pathophysiology, a heterogenous patient population, and a lack of clinical tools for risk stratification validated in this […]

CONCLUSION: Corticosteroids probably reduced short-term mortality and reduce the need for invasive mechanical ventilation in hospitalised patients with CAP.

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