Journal articles

BACKGROUND: Sleep disorders are common and costly to society. Guidelines from the American Academy of Sleep Medicine (AASM) and the Australasian Sleep Association (ASA) recommend Cognitive Behaviour Therapy for Insomnia (CBTi) as the best treatment modality for insomnia disorder in the long term, however, access issues due to medical first referral pathways and psychology workforce […]

CONCLUSION: This target trial emulation study suggests that a liberal transfusion threshold may provide a modest survival benefit during the early course of VA-ECMO, but no benefit afterwards. Prospective studies are needed to confirm these findings, assess clinical adoption, and investigate underlying mechanism.

Neonatal skin injuries are common, but location and metric size contribute to inconsistent severity reporting. To date, non-invasive technologies remain unexplored for neonatal injuries. The aim of this study was to assess the feasibility and accuracy of visual assessment against three technologies for injuries to the skin from pressure, stripping and tearing. The prospective diagnostic/feasibility […]

CONCLUSION: While high levels of awareness and confidence were reported, barriers continue to limit the translation of these positive attitudes into practice. Improved education and training materials delivered in multiple modalities and targeted at all levels of food service professionals are indicated.

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CONCLUSION: A decision aid significantly improved observer- and patient-rated SDM in primary care consultations for patients with SAPS. Observer-rated SDM scores more than doubled with the decision aid, and patients reported higher levels of SDM.

CONCLUSION: Ours is one of the largest prospective studies on UTD classification. Key points noted in this study are that most of the resolving UTDs were from UTD A1, and obstructive uropathies were from the UTD A2-3 group. Higher maximum APRPD and ureteric abnormalities were independent predictors for surgery in the UTD A2-3 group.

CONCLUSION: The evidence to guide clinical practice in the non-mechanical haemodynamic support of PE is severely limited. However, there are numerous candidate agents that could be further investigated. The high-risk group are an understudied population.

Infective endocarditis is a complex disease leading to significant morbidity and mortality. The in-hospital mortality has remained at 15-30% despite significant advances in cardiac imaging over the past two decades. Prevention, timely diagnosis, and prompt treatment can minimise adverse sequelae. The key to prevention lies in patient and clinician education. Traditionally the diagnosis has relied […]

BACKGROUND: Adolescents living with mental illness are more likely than their peers to engage in risky sexual behaviours such as unsafe sexual practices or drug misuse, which can result in sexually transmitted infections (STIs), unplanned pregnancies and sexual coercion or violence. One barrier to these adolescents receiving sexual and reproductive health (SRH) care is a […]

Human skin is a highly vascularized organ, where blood vessels perform essential roles in maintaining skin homeostasis and participate in thermal regulation. Currently, there is an unmet challenge to generate vascularized, functional skin models. In this study, human fetal placental endothelial colony forming cells (ECFC) are incorporated into human induced pluripotent stem cell (hiPSC)-derived skin […]

CONCLUSION: SDH represents a significant burden on regional neurosurgical services in Northern Australia. The findings underscore the challenges of delivering timely care across vast distances and the need for improved service models to support neurotrauma care in rural and remote settings.

CONCLUSION: We developed a priority set of 24 clinically relevant QIs for HNC, which will be tested in a clinical quality registry to benchmark optimal management of HNC and outcomes.

CONCLUSIONS: Variation exists in ECMO cannula dressing and securement practices across Australia and New Zealand intensive care units, and adherence to local guidelines is low. Further evidence on optimal cannula dressing and securement techniques is urgently required to inform the development of clinical practice guidelines and improve patient care and outcomes.