Journal articles

CONCLUSIONS: The findings in the UK cohort are consistent with the conclusions drawn from the global BLING III trial. It seems reasonable to conclude the finding are applicable to the UK.

CONCLUSIONS: The migration and malposition of peripherally inserted central catheters and umbilical venous catheters has significant costs and consequences. These should be targeted for evidence-based and innovative solutions to improve neonatal vascular access care.

All-cause pulmonary hypertension (PH) is associated with increased mortality and an enormous public health concern. However, given its complexity, multiple potential etiologies and inherent diagnostic challenges, PH diagnosis may be delayed or missed entirely. Artificial Intelligence (AI) shows potential to provide a simple but multifaceted, personalized approach for early identification of PH. AI-assisted patient triage […]

CONCLUSION: This ARIA 2024-2025 article supports patients, their caregivers, and healthcare professionals in choosing an intranasal treatment. However, decisions on AR treatment should consider the clinical variability of the disease, patients' values, and the affordability of medications.

CONCLUSION: Polymicrobial PJI remains a difficult condition to treat, with high morbidity requiring a tailored multidisciplinary approach. While standardized surgical and antibiotic strategies improve infection control, DTT organisms, and previous revision procedures increase the risk of recurrent infection. The poor long-term functional outcomes highlight the need for further optimization of treatment protocols to enhance patients' […]

CONCLUSIONS: Long term follow-up confirms durable responses with cemiplimab in patients with advanced CSCC in Australia treated on the EMPOWER-CSCC-1 trial.

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BACKGROUND: Up to 50% of individuals with musculoskeletal road traffic injury (RTI) develop chronic pain, resulting in substantial individual and societal burden. Integrated psychological and physical care, such as StressModex, improves patient outcomes compared to physical treatment alone. However, StressModex is not routinely implemented in physiotherapy practice, due to limited training access and physiotherapists' lack […]

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BACKGROUND: When conventional oxygen therapies fail, endotracheal intubation and invasive mechanical ventilation are the current standard of care in patients with acute hypoxaemic respiratory failure. However, invasive mechanical ventilation is associated with increased hospital and intensive care length of stay, healthcare costs, and morbidity and mortality. Inhaled nitric oxide has the potential to treat hypoxaemia […]

We write on behalf of the Collaboration of Aphasia Trialists and in response to an article recently published in the journal Brain Sciences: Quality of Assessment Tools for Aphasia: A Systematic Review by Panuccio and colleagues [...].

Robust data on trends in stroke hospitalisation rate and outcomes are needed to improve stroke care, yet are sparse and show conflicting results. We investigated the trends in hospitalisation rate, survival, and risk of stroke recurrence following an acute stroke using population-wide data from Australia and New Zealand over a 10-year period. We included adults […]

Extracorporeal life support (ECLS) is a high-risk, high-cost intervention that often entails prolonged ICU and hospital stays. Its rapid evolution raises crucial questions of appropriateness, proportionality, and value. Whereas much attention has focused on ECLS withdrawal, understanding when not to start is equally vital. Optimal ECLS care requires rigorous patient selection, clear evidence-based criteria, ongoing […]

Transfusion-related acute lung injury (TRALI) is a potentially fatal transfusion reaction. It can be caused by the transfusion of proteins, lipids, and extracellular vesicles that accumulate in blood components during routine storage and are collectively referred to as biological response modifiers (BRMs). It has been suggested that leucoreduction might reduce TRALI risk by limiting the […]