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Metro North is committed to providing a platform to acknowledge and promote research excellence within our health service. Below is a list of research publications from across our hospitals and services.
- Safety of Peripheral Vasoactive Drug Administration in Prehospital and Retrieval Medicine (SPOTLESS-2): A Prospective Observational Cohort Study 8 April 2026CONCLUSION: Our data suggests that adrenaline and noradrenaline may be safely administered peripherally in Prehospital and Retrieval Medicine environments, with a low overall risk of complications.Robbie Ley Greaves
- One-Year Retrospective Evaluation of Blood Administration Practices Within LifeFlight Medicine 8 April 2026CONCLUSIONS: PRBC transfusion within LFM is infrequent but essential across all missions. This analysis provides the first comprehensive Australian description of real-world PRBC utilisation across retrieval platforms, supporting transfusion governance, operational planning, and future outcome-focused research within Australia.Bradley Robert Richardson
- Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics 8 April 2026Crohn's disease (CD) is a chronic inflammatory condition of the bowel with a rising global incidence. Its complex etiology involves genetic susceptibility, environmental factors, and alterations in the gut microbiota, leading to dysregulated immune responses. Prompt diagnosis and personalized treatment are essential to prevent disease flares and complications. This review provides a comprehensive overview of […]Yoon-Kyo An
- Author response to commentary on oral microbiota analysis in HPV-infected individuals: considerations for future research 8 April 2026No abstractT I Maidment
- High-Flow Nasal Oxygen Therapy After Cardiac Surgery: A Randomized Clinical Trial 8 April 2026CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of HFNOT in patients at increased risk of postoperative pulmonary complications after nonemergent cardiac surgery, HFNOT did not improve DAH90 without increased support. These findings do not support the implementation of routine prophylactic HFNOT after cardiac surgery.Edward Litton
- Cost-effectiveness analysis of four sampling and genomic testing strategies for patients with advanced non-small-cell lung cancer in Australia 8 April 2026Molecular testing informs therapy selection for patients with non-small-cell lung cancer (NSCLC) providing access to better treatments. However, the costs and benefits of alternative specimens and testing options are unknown. We modelled the cost-effectiveness of four molecular testing strategies involving combinations of biopsy (tissue aspirate versus liquid), sample (formalin-fixed paraffin-embedded cell block, cytology smears or […]Louisa G Collins
- Introduction of the axial malalignment test: a classification system for torsional malalignment in the lower limb 7 April 2026Axial alignment of the lower limbs affects foot progression angle, knee biomechanics, patellofemoral joint instability, and hip impingement, although a standardized method of reference has not yet been described. An understanding of torsional malalignment is critical in many subspecialty areas of orthopaedics including paediatric orthopaedics, deformity correction, sports medicine, hip and knee surgery, as well […]Sheanna Maine
- Second primary invasive cutaneous melanomas in Queensland over 4 decades 7 April 2026Second primary invasive cutaneous melanomas (SPICMs) are common and pose an increased risk of death compared with single invasive melanoma only. Using data from the Queensland Oncology Repository, we investigated changes in the cumulative incidence of SPICMs for people diagnosed with a first primary invasive cutaneous melanoma between 1982 and 2022, with follow-up until December […]Danny R Youlden
- Innovation in intensive care: a framework to turn ideas and concepts into actionable solutions 7 April 2026CONCLUSION: This framework offers a pathway for innovation, supporting a more inclusive, effective, and sustainable future for intensive care.Maurizio Cecconi
- The feasibility of delivering and evaluating stratified care integrated with telehealth ('Rapid Stratified Telehealth') for patients with low back pain: a feasibility and pilot randomised controlled trial 7 April 2026CONCLUSION: This study provides important information to guide modifications to our Rapid Stratified Telehealth model of care and planning of a large multisite RCT across hospital outpatient clinics. Key Points • Our new model of care is feasible to deliver and evaluate in a fully powered RCT. • No intervention participant was at low risk […]Andrew R Gamble
- Clinical Handover as Craft, Not Checklist 6 April 2026Handover is one of the most studied elements of clinical care and its importance to the good continuity of care and patient outcomes is well-accepted. Unfortunately, efforts to improve the quality of clinical handovers have led to an environment of compliance exemplified by mnemonics, templates and audits that assume or suggest handovers to be stable, […]Aloha Hufana Ambe
- Machine learning to predict long-term cardiovascular death following myocardial infarction: incremental value of echocardiographic data 6 April 2026CONCLUSION: ML integration of comprehensive echocardiographic data leads to improved prediction of CV death following MI, with key measures of LV size and systolic and diastolic function contributing substantially to prognostic models.Liam Scanlon
- Correction to: Circulating tumour cells and circulating tumour DNA in head and neck cancer: from molecular insights to clinical impact 6 April 2026No abstractSreedevi Damodaran
- Optimising peripheral intravenous catheter insertion in the emergency department: systematic review protocol 6 April 2026CONCLUSION: This review will identify techniques and technologies that improve PIVC insertion success and function in the ED. By analysing pooled outcomes, the researchers aim to provide recommendations to enhance PIVC insertion success, and ultimately patient outcomes. Identifying effective methods will also highlight key areas for future research.Fiona M Daglish
- Consent-to-continue in intensive care clinical trials: A scoping review and recommendation for reporting 5 April 2026CONCLUSIONS: Despite many jurisdictions allowing CTC, it is still uncommon in ICU RCTs. These results will inform the development of future processes and materials to enhance understanding, implementation and reporting of CTC.Kristen S Gibbons
