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Metro North is committed to providing a platform to acknowledge and promote research excellence within our health service. Below is a list of research publications from across our hospitals and services.
- Correction: Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study 28 March 2025No abstractAndrew J Simpkin
- Evaluating the HELIX4 implementation capacity-building program 28 March 2025CONCLUSIONS: The HELIX4 program enhanced participants' knowledge, confidence, and organizational support for evidence implementation. The pilot provides a foundation for future iterations of the program, with a focus on addressing long-term sustainability and time management challenges.Jed Duff
- Mental Health Profile Relating to Suicide Crises Among Women in and Around Pregnancy and Surgical Termination of Pregnancy: A Data Linkage Study 28 March 2025CONCLUSION: Findings present a complex picture of the relationship between mental health diagnosis, pregnancy or termination of pregnancy, and other stressors experienced around the time of a suicide-related contact with police or paramedics.Carla Meurk
- Returning to work following parental leave: the experiences of Australian anaesthetists 28 March 2025With increasing gender balance in specialist medical training and employment in Australia, there is a corresponding need to consider how parental leave and subsequent return to work is managed in the workplace. An electronic survey exploring the experiences of pregnancy and return to work following parental leave was distributed by the Australian and New Zealand […]Isabelle L Cooper
- Cefazolin versus placebo for surgical antibiotic prophylaxis in low-risk cesarean delivery: a feasibility blinded randomized controlled trial 27 March 2025CONCLUSIONS: Feasibility was impacted by the high-risk population and patient desire for antibiotics. Adherence to perioperative infection prevention practices were high but incomplete. These study processes could be effectively applied in a larger population, targeting low risk maternity patients.Victoria A Eley
- Mean arterial pressure in critically ill adults receiving vasopressors: A multicentre, observational study 27 March 2025CONCLUSIONS: In a large, multicenter study of heterogeneous critically ill patients on vasopressors, the mean hourly MAP was > 70 mmHg. This mean hourly MAP was observed consistently over diverse clinical subgroups and is higher than recommended by guidelines.Kyle C White
- Feasibility and acceptability of a remote computerized cognitive training employing telehealth in older adults with subjective cognitive complaints 27 March 2025INTRODUCTION: Computerized cognitive training (CCT) represents promising solutions for remote training of cognitive abilities in older people with cognitive decline. In the present article, we tested the feasibility and acceptability of a CCT performed at home via a telehealth platform, with participants connected remotely to a clinician, in comparison to an in-person CCT.Marion Ferrandez Y Montesinos
- Appetite loss in patients with motor neuron disease: impact on weight loss and neural correlates of visual food cues 27 March 2025Motor Neuron Disease (MND) is associated with significant non-motor symptoms, including the loss of appetite. Loss of appetite has emerged as a dominant feature of the disease that may contribute to negative energy balance, faster disease progression and earlier death. We examined the prevalence and impact of appetite loss and analysed neural correlates of visual […]Jeryn Chang
- Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients 27 March 2025CONCLUSION: LT recipients receiving protocolized antiresorptive treatment post-LT had a low incidence of osteoporotic fracture.Elisabeth Ng
- Telomeropathy: pretransplant and posttransplant considerations for clinicians 27 March 2025PURPOSE OF REVIEW: This review examines the current understanding of telomere biology disorders (TBDs) in advanced lung disease, with particular focus on their implications for lung transplantation outcomes and management.John A Mackintosh
- Urinary EGF: Back to the Future 27 March 2025No abstractMonica Suet Ying Ng
- Prevalence and Medium-Term Outcomes of Patients with Biopsy-Proven Intermediate- to High-Risk Prostate Adenocarcinoma with Low Intraprostatic Uptake on [<sup>68</sup>Ga]Ga-PSMA-11 PET/CT in the proPSMA Study 27 March 2025The current prevalence of low intraprostatic uptake for staging prostate-specific membrane antigen (PSMA) PET ranges between 4.4% and 17% in retrospective studies. We aimed to define the prevalence and describe the outcomes of patients with low intraprostatic uptake on PSMA PET/CT in the prospective proPSMA study. Methods: We identified patients with an SUV(max) of 4 […]David C Chen
- What are the broader impacts and value from a randomised controlled trial conducted in six public hospital antenatal clinics in Australia? An impact assessment using the Framework to Assess the Impact from Translational health research 26 March 2025CONCLUSION: This case example in the developing field of impact assessment illustrates how researchers can use evidence to demonstrate and report more broadly on the impact of and returns on research investment in a clinical trial.Elissa Elvidge
- False hope of a single generalisable AI sepsis prediction model: bias and proposed mitigation strategies for improving performance based on a retrospective multisite cohort study 26 March 2025CONCLUSIONS: Implementing a single sepsis prediction model across all sites and care locations within multihospital systems may be unacceptable given large variances in NNE across multiple sites. Bias mitigation methods can identify models demonstrating improved performance across most sites in reducing alert burden but with no impact on the length of the prediction window.Rudolf Schnetler
- Defining Voltage Mapping Thresholds for Multielectrode Catheters: Extrapolation or Bespoke Precision? 26 March 2025No abstractHaris M Haqqani