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Metro North is committed to providing a platform to acknowledge and promote research excellence within our health service. Below is a list of research publications from across our hospitals and services.
- Central Venous Access: An Update on Modern Techniques to Avoid Complications 28 May 2025Background: Central venous catheterization (CVC) is a frequently performed procedure in anesthesia and critical care settings. Modern procedures have improved significantly, particularly with increasingly sophisticated venous verification methods and ultrasound guidance. While the associated historical complication rates reflect this improvement, complications such as inadvertent arterial puncture, arterial cannulation, pneumothorax, deep vein thrombosis, and catheter-associated infection […]Kai Woodfall
- Thoracic Society of Australia and New Zealand (TSANZ) Guidance for the Management of Electronic Cigarette Use (Vaping) in Adolescents and Adults 28 May 2025Electronic cigarette (EC) use, especially among younger members of society, has grown to concerning levels in many countries, including Australia and New Zealand. Uptake in the general population, driven by technological and pharmacological innovations, and accelerated by aggressive tobacco/vaping industry marketing, has outpaced medical research. As the harms of EC use become increasingly evident, the […]Henry Marshall
- Modelling and Simulation of the Interactions Between the Cardiovascular System and the Combined Use of VA ECMO and IABP: Comparison Between Peripheral and Central Configurations 28 May 2025Veno-arterial extracorporeal membrane oxygenation (VA ECMO) for the management of refractory cardiogenic shock (CS) has been widely used in recent years. Increased left ventricular (LV) afterload induced by retrograde flow remains a limiting factor, which is particularly evident during peripheral VA ECMO support. The concomitant use of the intra-aortic balloon pump (IABP) is an established […]Beatrice De Lazzari
- Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre survey 28 May 2025CONCLUSIONS: This study revealed significant variation in OPAT practice. Further study is needed to understand the reasons for these differences and whether better alignment of practice could improve patient outcomes, antimicrobial stewardship practice and resource utilization.Zenaw T Wolie
- The transformative potential of remote patient monitoring in health care 28 May 2025No abstractTuan Duong
- Heat Loss During Procedural Sedation for Endoscopy: A Descriptive Study 28 May 2025CONCLUSIONS: Patients receiving procedural sedation for endoscopic procedures may experience heat loss comparable to the initial phase of general or neuraxial anesthesia. Active warming and continuous temperature monitoring are yet to be implemented in this population.Judy Munday
- Post-traumatic stress disorder specific to parents in the neonatal intensive care unit 28 May 2025CONCLUSIONS: The use of the PTSD Checklist for DSM-5 administered by neonatal nurses can help identify potential signs of parental stress or trauma. Further research must assess whether early screening and referral improve parental outcomes.Lisa McKeown
- An open letter to the ISHLT and its global lung transplantation community 28 May 2025No abstractPaul A Corris
- A System for Verifying Radiation Therapy Treatments That Use Multiple Modes of Real-Time Motion Adaptation 27 May 2025This technical report describes the development and use of a system for performing routine quality assurance (QA) of real-time adaptive radiotherapy treatments delivered using the Accuray Radixact Synchrony platform. Established international guidelines recommend the use of a dynamic phantom to verify real-time target tracking and the use of 2D dosimetry to verify the accuracy of […]Tanya Kairn
- Ambulance transport to hospital in patients with a palliative ambulance management plan 27 May 2025The palliative ambulance management plan (AMP) is a document that assists paramedics in the acute care of patients with life-limiting illness. We retrospectively examined ambulance attendances for 111 patients with an AMP in the Hutt Valley, New Zealand. Ambulances attended 46 patients on 67 occasions with 40% transported to an acute hospital. Transport preferences were […]Jessica Luey
- Peptide receptor radionuclide therapy in malignant insulinoma 27 May 2025Management of malignant insulinoma (MI) presents dual management challenges of hypoglycaemia and tumour control. This study aims to analyse long-term outcomes of PRRT for treatment of MI. We retrospectively reviewed consecutive patients with MI treated with [177Lu]Lu-DOTATATE (LuTATE) at two Australian NET centres between 2004-2022. Follow-up for hypoglycaemia, molecular imaging, radiologic and biochemical responses, treatment-related […]David A Pattison
- Stopping syphilis on the streets: embedding point of care testing within a street outreach nursing service 27 May 2025Background Nationally, the increase in syphilis notifications over recent years has demonstrated persistent bridging across to wider populations, particularly women of reproductive age. Populations experiencing adverse social determinants, caught in a cycle of marginalisation and social exclusion through mental ill-health, alcohol and drug misuse, and economic and housing stress, have increasingly become susceptible. Methods The […]Leanne Papas
- Health related quality of life in the UK Biobank Experience of Pain follow-up study: a comparison with general population norms 27 May 2025The UK Biobank (UKB) is a population-based resource of genetic, health, lifestyle, sociodemographic, and linked clinical data for ~500,000 volunteers. Previous analyses of health determinants have shown that the UKB is not representative of the population from which it is drawn. However, representativeness from a general health-outcomes perspective is unknown, but could be assessed using […]N R Armfield
- The cost-utility of targeted germline BRCA testing in localised prostate cancer followed by cascade testing first-degree relatives with pathogenic variants 26 May 2025CONCLUSION: Germline BRCA testing may not be cost-effective when limited to patients with localised PCa but demonstrates value for money when extended to FDRs.Srinivas Teppala
- Safety and Sample Adequacy for Comprehensive Biomarker Testing of Bronchoscopic Biopsies: An American Association of Bronchology and Interventional Pulmonology (AABIP) and International Association for the Study of Lung Cancer (IASLC) Clinical Practice Guideline 26 May 2025Linear endobronchial (EBUS) guided sampling of accessible mediastinal lesions is well established as a first-choice modality for lung cancer mediastinal staging. Parenchymal lung lesions, however, are routinely accessed by either a percutaneous (CT-guided) or a bronchoscopic approach. Direct comparisons between the percutaneous approach and bronchoscopy, or EBUS and mediastinoscopy are sparse in regard to diagnostic […]Udit Chaddha