Journal articles

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CONCLUSIONS: COMFORTER improved post-MET risk stratification compared with REMAIN and NEWS using fewer routinely available variables. The model consistently identified patients at higher risk despite variation in absolute risk estimates across hospitals. The model may support team communication and decision-making for prioritising post-MET care.

CONCLUSION: In this exploratory and hypothesis-generating analysis, a small subset of patients with relapsing AAV showed suboptimal outcomes with rituximab. Residual disease activity at month 4, particularly in patients with PR3-ANCA positivity and ENT involvement, may represent a clinical subgroup associated with an increased frequency of earlier relapse, although this observation requires confirmation.

CONCLUSIONS: These priorities provide a stakeholder-informed foundation for future intensive care research, supporting collaborative research programs, funding strategies, and meaningful researcher-clinician-consumer partnerships.

CONCLUSIONS: We discuss limitations and confounders and, critically, give voice to the people living with a lobular breast cancer diagnosis.

CONCLUSION: IFIs in heart transplant recipients frequently occur beyond the first year posttransplant. Higher Charlson scores were associated with reduced survival. These findings support the need for tailored prophylaxis strategies and improved diagnostic algorithms in preventing posttransplant IFI.

Lemierre's syndrome and base-of-skull osteomyelitis can occur together in immunocompetent adolescents with Arcanobacterium haemolyticum bacteraemia. Prolonged high-dose ceftriaxone may precipitate symptomatic cholecystitis. Clinicians should consider A. haemolyticum as a causative pathogen in invasive head and neck infection, including Lemierre's syndrome and osteomyelitis, even in immunocompetent hosts.

CONCLUSION: Optimized BOLD fMRI protocols effectively minimized susceptibility artifacts while preserving image quality, enabling reliable functional imaging in DBS patients-a timely advancement given the rise in DBS implants and introduction of directional stimulation systems.

CONCLUSION: Water conservation in haemodialysis appears feasible through reduced dialysate flow and reject water reuse, although the magnitude of gross mains water savings depends on reverse osmosis system efficiency and local infrastructure. Evidence is primarily single centre and heterogeneous; further standardised reporting and long-term clinical, operational, environmental and implementation studies are needed.

The clinical management of patients with brain tumors, as well as the results of clinical trials testing new medications, require the evaluation of tumor changes on MR imaging. After tumor measurements are obtained, the AIRES software application can automatically apply the standardized RANO rules, to ultimately define when the tumor can be considered in a […]

CONCLUSIONS: RO has rapidly adopted software-based and AI-enabled technologies, yet recall frequency has remained stable, which may potentially obscure software-related safety risks. These findings underscore the need for continued postmarket surveillance, rigorous commissioning and revalidation, lifecycle oversight, and clinician education. This study also provides a contemporary benchmark to inform patient safety strategies as the field […]

CONCLUSIONS: Commercially available self-warming chemical blankets exhibit a dual failure: they are too slow to provide therapeutic warming within the acute treatment window and generate surface temperatures consistent with serious burn risk under prolonged contact, particularly in patients with impaired peripheral circulation or reduced consciousness. The absence of a dedicated safety standard for this device […]

Small GTPases of the Ras superfamily are critical regulators of diverse cellular processes. While crosstalk between their signalling pathways has been documented in animals, similar mechanisms remain unexplored in plants, where small GTPases have undergone unique evolutionary diversification. Here we identify REAP1/AtSWAP70 as an effector in Arabidopsis thaliana that interacts with the active forms of […]

A man in his 40s undergoing long-term otolaryngology surveillance following an initial diagnosis of a left-sided nasopharyngeal lesion classified as carcinoma in situ re-presented approximately 3 years later with intermittent aural fullness and tinnitus. Flexible nasendoscopy demonstrated subtle unilateral polypoidal change at the left eustachian tube orifice and fossa of Rosenmüller (FOR), while MRI remained […]

CONCLUSIONS: The incidence of GBS and Enterobacterales BSI has risen in young infants in Queensland, especially for early-onset GBS since 2014. These findings highlight the increasing importance of Enterobacterales infections in young infants and the need to reconsider prevention strategies for early-onset GBS.