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Metro North is committed to providing a platform to acknowledge and promote research excellence within our health service. Below is a list of research publications from across our hospitals and services.
- Current and emerging strategies for the manufacture, implantation, and clinical management of corneal tissue allografts 9 December 2024Approximately 40,000 Australians have received a donor corneal tissue transplant over the last 40 years, with the primary indications being keratoconus, Fuchs' endothelial dystrophy, bullous keratopathy, and failure of a prior corneal transplant. Although corneal cross-linking and rigid contact lenses have emerged as alternative strategies for the management of keratoconus, the demand for donor corneas […]Jennifer A Walshe
- Integrating evidence from lived experience of Aboriginal people and clinical practice guidelines to develop arthritis educational resources: a mixed-methods study 8 December 2024BACKGROUND: Globally, osteoarthritis, rheumatoid arthritis, and gout (arthritis conditions) result in considerable pain and suffering and disproportionately affect First Nations Peoples, who are more likely than non-First Nations Peoples to have an arthritis condition and to experience a higher burden of disease. Access to culturally appropriate health information supports the health and wellbeing of First […]Brooke Conley
- Health system related kidney supportive care interventions for adults with chronic kidney disease: A systematic review 6 December 2024CONCLUSIONS: The studies highlighted the effectiveness of kidney-supportive care interventions in improving patient outcomes, especially in end-of-life care and symptom management. However, significant existing gaps identified necessitate further research.Dilantha Dharmagunawardene
- Clinicians' views on implementing enhanced recovery after surgery: a descriptive qualitative study 6 December 2024CONCLUSION: Motivational strategies are required to inspire individual clinicians to adopt ERAS. Additionally, resources are needed for ERAS to guide practice and support implementation (i.e., staffing and time), underscoring the need for hospital leadership support.Georgia Tobiano
- Ceasing or gradually reducing incubator humidity after 7 days for extremely preterm infants: a randomised clinical trial 6 December 2024CONCLUSIONS: Ceasing or gradually reducing incubator humidification after day 7 of life had no effect on the number of episodes of hypothermia or hyperthermia in this cohort of extremely preterm infants (EPTI). There was also no effect on the number of episodes of hyponatraemia or hypernatraemia.Gillion Noreiks
- The Use of a Digital Well-Being App (Stay Strong App) With Indigenous People in Prison: Randomized Controlled Trial 6 December 2024CONCLUSIONS: We believe this to be Australia's first evaluation of a digital mental health app in prison and the first among Indigenous people in custody. While the study demonstrated that the use of a well-being app within a prison was feasible, staff shortages led to delayed recruitment and a consequent low retention, and significant beneficial […]Elke Perdacher
- Pathogen genomics in healthcare: overcoming barriers to proactive surveillance 5 December 2024Pathogen genomic surveillance in healthcare has the potential to enhance patient safety by detecting outbreaks earlier, thereby reducing morbidity and mortality. Despite benefits, there are barriers to adoption, including cost, expertise, and lack of standardized methodologies and incentives. This commentary advocates for 1) investment from healthcare payors, public health, and regulatory bodies and 2) additional […]Alexander J Sundermann
- Routine blood biochemical biomarkers in amyotrophic lateral sclerosis: Systematic review and cohort analysis 5 December 2024Introduction: Blood biochemical biomarkers, including urate, creatinine, albumin, and creatine kinase, have been shown to be useful in ALS. To provide further information about the roles of these four biomarkers roles we performed a systematic review. In addition, we also performed a new study of the role of these biomarkers in predicting survival, using data […]Robert J Nona
- Uncovering language deficits in focal epilepsy: Beyond the limits of noun naming and verbal fluency 5 December 2024CONCLUSIONS: Our results show that current approaches to language assessment are inadequate for identifying language impairments in people with focal epilepsy, and likely underestimate the prevalence of language impairment in this population. In particular, verb naming and picture description subtests revealed deficits across the majority of the sample, highlighting the need for more comprehensive assessment […]A D Reardon
- Insights into antithrombotic therapy in pregnancy 5 December 2024No abstractBibi A Bassa
- In-person, virtual visiting and telephone calls in Australia and New Zealand intensive care units: A point prevalence multicentre study mapping daytime and nighttime interactions 5 December 2024CONCLUSIONS: In a low COVID-19 prevalence period, Australia and New Zealand ICUs had partially reopened to visitors. Most visits happened during the day and evening but persisted overnight. ICU resourcing and visiting policies should take these data into account to facilitate family presence at the bedside, virtual visiting, and obtaining clinical updates via telephone.Alexis Tabah
- Approach to otitis externa in Australian general practice 4 December 2024BACKGROUND: Acute otitis externa (AOE) is an inflammatory condition of the outer ear seen in Australian general practice and is prevalent in tropical climates like North Queensland.Jeremy Lee
- Modular design workflow for 3D printable bioresorbable patient-specific bone scaffolds: extended features and clinical validation 4 December 2024A previously in-house developed patient-specific scaffold design workflow was extended with new features to overcome several limitations and to broaden its adaptability to diverse bone defects, thereby enhancing its fit for routine clinical use. It was applied to three clinical cases for further validation. A virtual surgical resection tool was developed to remove regions of […]Buddhi Herath
- Nurse-surgeons in the Australian public health system: A descriptive quantitative survey 4 December 2024CONCLUSIONS: Nurse-surgeons have been practicing in Australia for decades, yet no standard training and credentialing pathway exist for them. This study identified the various roles, non-standard training, and perceptions of nurse-surgeons in the Australian public health system. The findings of this study will have an impact on policymakers and stakeholders to develop standard national credentialing […]Tenber Grota
- Adjuvant rituximab and elevated intratumoural CD8 expression are associated with sustained disease control after radiotherapy in a randomised trial of systemic therapy in early-stage follicular lymphoma 4 December 2024BACKGROUND: We report extended follow-up of TROG99.03, a randomised phase III trial in early-stage follicular lymphoma (ESFL) including new information on the role of adjuvant rituximab and translational studies.Michael P MacManus