Journal articles

Animal models of critical illness span diverse species and experimental approaches, reflecting the biological complexity of severe disease states while being constrained by animal welfare requirements and country-specific regulatory, infrastructural, and workforce factors. Persistent challenges remain, including limited reproducibility, fragmented standards, and the need for ethical alignment across borders. This review examines these shared structural […]

Access to mycological diagnostics varies across clinical laboratories. This study aimed to assess the availability of key fungal diagnostic methods in Australia and New Zealand. A survey was distributed to infectious disease physicians, clinical microbiologists (including trainees), and laboratory scientists across Australia and New Zealand. It covered institutional characteristics, perceived common fungal pathogens, and access […]

CONCLUSION: Despite outstanding and high-quality colonoscopy services being provided, higher than recommended colonoscopy surveillance was identified in the regional public hospitals in Central Queensland. Hospital processes should be improved to ensure appropriate intervals between procedures to avoid using scarce healthcare resources.

This report details the long-term follow-up of a patient previously reported from our centre with recurrent acute pancreatitis and episodic jaundice in the setting of three rare anatomic variants: gallbladder agenesis, ansa pancreatica, and a santorinicele. The index report described progressive main pancreatic duct dilatation and endoscopic findings consistent with intraductal papillary mucinous neoplasm (IPMN) […]

CONCLUSION: The formation of a statewide HAPI prevention program coincided with a sizeable reduction in HAPI prevalence. This evaluation demonstrates that large-scale quality improvement programs to reduce HAPIs can be effective and sustainable.

CONCLUSIONS: Adoption of and adherence to the evidence-based recommendations in this consensus statement should reduce clinical variation. Ultimately, this should lead to system-level improvements in quality of care and outcomes for patients undergoing TIPS implantation. These recommendations summarize the complete document, available at https://www.gesa.org.au/resources/ .

CONCLUSIONS: TA may reduce failure, overall complications and dislodgement for PIVCs in children, but no benefit was observed for CVADs. Larger RCTs using standardized methods are needed to strengthen the evidence.

Lymph node dissection has been a component of surgical staging for endometrial cancer, with more recent change to sentinel lymph node biopsy as standard of care. However, comparisons of any lymph node assessment with no nodal assessment is limited. We conducted a systematic review of literature published between June 2015 and July 5, 2025, searching […]

CONCLUSION: In Australia and New Zealand, national EviQ guidelines are used more often than the MASCC/ISOO guidelines. Feasibility for implementing palifermin and photobiomodulation should be reassessed, and greater collaboration in developing guidelines is necessary.

Individuals with a family history of premature coronary heart disease (CHD) have increased cardiac morbidity and mortality, which may motivate them to modify their health behaviours. This analysis examines whether patients with self-reported family history of premature CHD experiencing an acute coronary syndrome (ACS) were more likely to have their risk factors and health behaviours […]

COASY protein associated neurodegeneration is a rare, progressive autosomal recessive neuroferritinopathy due to pathogenic mutations in the COASY gene, coding for the mitochondrial located coenzyme A synthase. Clinical manifestations include seizures, progressive spasticity, dystonia, neuropathy, cognitive decline and neuropsychiatric abnormalities. Both foetal and childhood onset phenotypes are described. We report three patients with COASY protein […]

CONCLUSION: NOAF was common amongst patients admitted to the ICU, and amiodarone is commonly prescribed. Future studies are required to determine the optimal short- and long-term management strategies for NOAF complicating critical illness.

CONCLUSIONS: Observed mortality of patients retrieved and treated with ECMO was lower than mortality predicted by SAVE and RESP scores.

CONCLUSIONS: The findings from this study suggest varied hemodynamic and flow dynamic outcomes when comparing CF and PF VA ECMO, each with their own benefits and drawbacks.

INTRODUCTION: Losses of functional reserve across multiple physiological systems have been identified in frail patients, yet the exact aetiology of frailty remains unclear. Although strongly associated with chronological age, frailty often develops at a younger age in patients with organ failure. Frailty is prevalent in patients with kidney failure; however, individuals experience improvements in physical […]